Glycogen Storage Disease

Jubiz and Rallison, Archives of Internal Medicine (1974), ¹¹⁹³ report on four patients with glycogen storage disease, two with debranching enzyme system deficiency, one with phosphorylase deficiency and one with glucose-6-phosphatase deficiency. These patients were treated with PHT for more than two years and there was a good response. This was evidenced by a reduction in liver size and hepatic glycogen content. Hyperlacticacidemia improved.

1193. Jubiz, W. and Rallison, M. L., Diphenylhydantoin treatment of glycogen storage diseases, Arch. Intern. Med., 134: 418-421, 1974.